MK-2866 (Ostarine)

Descriptions and Benefits

MK-2866, also known as Ostarine is one of the best-studied SARMs. It is a non-steroidal selective androgen receptor modifier that strengthens muscle and tendons. Does not have the negative side effects associated with testosterone such as raising liver, kidney, and prostate enzymes. Elderly men and women who took modest doses of Ostarine for 12 weeks grow 3 pounds of muscle and lost a pound of fat, with no changes to diet or exercise.

Half Life

24 hours.

Normal Concentration

25mg

Side Effects

Minor testosterone suppression. Minimal PCT is recommended.

LGD-4033 (Ligandrol)

Descriptions and Benefits

LGD-4033, also known Ligandrol, is a SARM that has been shown to have positive effects on muscle building, body recomposition, and bone density. Ligandrol has been shown to be highly selective for muscle and bone cells, largely ignoring prostate or sebaceous cells, makes the side effects for LGD-4033 minimal.

Half Life

24 - 36 hours.

Normal Concentration

10mg

Side Effects

Ligandrol is more suppressive of endogenous testosterone and sex hormone-binding globulin than other SARMs, making a full post-cycle therapy necessary.

GW-501516 (Cardarine)

Descriptions and Benefits

GW-501516, also known as Cardarine, is not hormonal so it is not suppressive of endogenous testosterone. It has been shown to have positive effects on muscle building, endurance, and body recomposition. GW-501516 on its own has been found to activate many of the genes that activate when an organism goes for a run or exercises.

Half Life

20 - 24 hours.

Normal Concentration

10mg

Side Effects

The most controversial reported side effect is increased cancer incidence. Out of many studies on Cardarine, used a dose one hundred times larger than the normal dose for over 10 times as long as the research chemical is typically used. This “side effect” is highly disputed. More in-depth studies have found that Cardarine actually reduces tumor size.

MK-677 (Nutrobal)

Descriptions and Benefits

MK-677, also known as Nutrobal, is commonly react as a Human Growth Hormone that it stimulates the pituitary gland to secrete HGH. MK-677 has been shown to increase fat-free mass, enhance sleep quality, improve healing of muscle, and ligaments. It is also improve hair, skin appearance and improve overall sense of well-being. There are no chances of aromatization, or danger to liver, kidney, or prostate.

Half Life

24 hours.

Normal Concentration

25mg

Side Effects

Slight increase in appetite and numb hands has been noticed. MK-677 has been used continuously for 1-2 years with no sign of desensitizing the pituitary gland.

RAD-140 (Testolone

Descriptions and Benefits

RAD-140, also known as Testolone has the highest ratio of anabolic to androgenic activity of any SARM discovered, 90:1. Testosterone has an anabolic to androgenic ratio of 100:100. This means that Testolone is almost as anabolic as testosterone while being only 1/100th as androgenic. This is a positive as most of the negative side effects of testosterone, including effects on liver, kidney and prostate, come from its androgenic effects.

Half Life

16 hours.

Normal Concentration

15mg

Side Effects

None to date, including no effects on liver, kidneys, prostate, nor aromatase conversion (conversion of testosterone into estrogen).

S4 (Andarine)

Descriptions and Benefits

S4, also known as Andarine, is a SARM that selectively binds to androgen receptors in skeletal muscle tissue. There is little danger of non-skeletal muscle tissues experiencing androgen activity.  Additionally, research has shown it does not cause aromatization (conversion of testosterone into estrogen), liver strain, or severe HPTA (hypothalamic pituitary testicular axis) suppression. Aside from building lean body mass, Andarine is also used for benign prostatic hypertrophy, muscle wasting, and osteoporosis.

Half Life

4-6 hours.

Normal Concentration

50mg

Side Effects

High dosages may result in short-term changes in vision due to a metabolite of S4 binding to vision receptors. Changes go away after the SARM is no longer in the system. Mini post cycle therapy regiment is required; the recovery time is only 2-3 weeks after completion.

SR9009 (Stenabolic)

Descriptions and Benefits

SR9009, also known as Stenabolic, that influences lipid and glucose metabolism in the liver and the creation of fat-storing cells. Stenabolic has been found to increase mitochondria, the powerhouses of your cells. Once mice were given Stenabolic, they were able to run for 50% longer than non-treated mice. It has also been found to aid weight loss.

Half Life

3 hours.

Normal Concentration

20mg

Side Effects

There are no known side effects, including no known suppression of endogenous testosterone as Stenabolic is not a hormonal drug.

YK-11 (Myostatin Inhibitor)

Descriptions and Benefits

YK-11 although lumped into the SARM category is actually a myostatin inhibitor. Myostatin inhibits muscle growth. By inhibiting the inhibitor, YK-11 promotes rapid muscle growth. YK-11 has been shown to be more anabolic than dihydrotestosterone (DHT). Although just discovered in 2011, YK-11 is quickly developing a reputation as the most powerful SARM.

Half Life

6-10 hours.

Normal Concentration

10mg

Side Effects

Mild, reversible liver impairment. There has been no noted endogenous testosterone suppression.

S23

Descriptions and Benefits

S23 belongs to a new class of drugs called selective androgen receptor modulators (SARM). Similar to testosterone and other SARMs, S23 targets the muscle and bone tissues to promote muscle growth and bone health. S23 does not target the prostate tissue so it does not cause prostate enlargement. S23 is becoming increasingly popular in the bodybuilding community. It is allegedly effective at increasing muscle mass and decreasing fat all while having minimal side effects.

Half Life

12 hours.

Normal Concentration

10mg

Side Effects

Mild, reversible liver impairment. There has been no noted endogenous testosterone suppression.